what's wrong
英 [wɒts rɒŋ]   美 [hwɑts rɔːŋ]  
怎么了;怎么回事;你怎么了

例句：
What's wrong with him? 

他怎么了？

What's wrong? why do you wear a long face? 

你怎么了？你为什么哭丧着脸？

What's wrong with a bit of smoodge between friends? 

朋友之间互相恭维一下有什么不妥？

You look wretched ─ what's wrong? 

你看起来愁眉苦脸的，怎么啦？